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Sengottuvelan Murugan

Sengottuvelan Murugan headshot.

Research Associate
Endocrine Research Facility

Curriculum Vitae (200k PDF)



My primary research interests lie in the areas of immuno-oncology and neuroimmunology along with cancer chemotherapeutics. Although significant advances have been made in the field of cancer research in recent years, the disease is still leading causes of death worldwide due to its ability to metastasize and develop resistance to current therapies. Therefore, there is an urgent need to develop novel approaches that not only prevent the progression of cancer but also overcome resistance to new drugs. Throughout my graduate and postdoctoral training, I have been particularly interested in studying signaling pathways that are associated with cancer development, progression, metastasis, and resistance.

More recently, I was part of the molecular biology program focusing on characterizing and developing genetic and chemical approaches to modulate targeted and immune checkpoint inhibitor resistance in advanced melanoma patients. I was also involved in the establishment of melanoma patient-derived xenograft (PDX) models which resemble the original patient tumors closely in tissue architecture, genotype, and heterogeneity.

My research in the coming years will focus on repurposing and how drugs can be combined with existing therapies for preventing the growth and resistance of various types of cancer. We believe that new therapeutic combinations will make improvements in cancer therapy and overcome resistance. My overall career objective is to investigate and develop novel approaches for the treatment of a variety of cancer including breast, melanoma, and lung in pre-clinical models and translate my discoveries into effective therapies for patients.


Title Location Year
Research Associate Deptartment of Animal Sciences
Rutgers University
2017 - present
Postdoctoral Fellow Perelman School of Medicine
University of Pennsylvania
2015 - 2017
Postdoctoral Research Associate Deptartment of Animal Sciences
Rutgers University
2009 - 2015
JSPS Postdoctoral Fellow Hokkaido University, Japan 2007 - 2009
Assistant Researcher Hokkaido University, Japan 2006


Degree Location Year
Postdoc Hokkaido University, Sapporo, Japan 2007 - 2009
Ph.D. Biochemistry
Annamalai University, Tamilnadu, India
M. Phil. Biochemistry
Pondicherry University, Pondicherry, India
M.S. Biochemistry
Annamalai University, Tamilnadu, India
B.S. Biochemistry
Bharathiar University, Tamilnadu, India